Anti-RGS1 Antibody

This polyclonal reagent from Antibodies.com is raised in rabbit hosts and is supplied as an unconjugated 100 µl volume, supporting Western blot and ELISA workflows in immunology and cell signaling research. It detects RGS1 (Regulator of G-protein Signaling 1), a roughly 24 kDa GTPase-activating protein that accelerates GTP hydrolysis on Gα subunits to attenuate GPCR signaling. The antibody cross-reacts with samples from human, mouse, and rat origin, enabling comparative studies of lymphocyte migration, B-cell trafficking through germinal centers, and chemokine receptor desensitization.

The unconjugated format gives researchers flexibility for custom fluorophore or enzyme conjugation and direct immunoblotting. On Western blots, the target typically resolves near 24 kDa, with apparent shifts possible due to phosphorylation or other post-translational modification. Recommended handling includes short-term refrigerated storage, aliquoting upon arrival to limit freeze-thaw cycles, and protection from light. Intended for research use only in laboratory settings such as flow cytometry, immunohistochemistry, and standard immunoblotting.