Anti-RGMB Antibody

Raised in rabbit against repulsive guidance molecule B, this polyclonal antibody from Antibodies.com targets a GPI-anchored protein with documented roles in BMP signal transduction and in PD-L2-mediated costimulation of T lymphocytes. Supplied as 100 µl of unconjugated antiserum, the reagent is validated for western blot and immunohistochemistry on human samples. RGMB expression is reported in mucosal epithelium and in the central nervous system, where it is studied in the context of bone morphogenetic protein signaling, neural tube patterning, and respiratory immune tolerance. Researchers working on the PD-L2/PD-1 axis also use this antibody to profile RGMB distribution in tumor sections and to confirm upregulation in transfected cell lines by immunoblotting. The unconjugated format allows flexible pairing with secondary reporters such as HRP, biotin, or fluorophore conjugates depending on the assay design.