Anti-RGMB Antibody

This rabbit polyclonal reagent from Antibodies.com targets RGM domain family member B (RGMB), a GPI-anchored co-receptor that modulates bone morphogenetic protein (BMP) signaling and influences T-cell costimulation in published immunological and neurodevelopmental studies. The antibody is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, as an unconjugated preparation that allows flexible downstream labelling depending on the assay.

Validated for Western blot on human, mouse, and rat samples, the polyclonal host response gives broad epitope coverage for detecting endogenous RGMB in cell lysates and tissue homogenates. Researchers commonly apply it to investigate BMP pathway activity in bone biology, T-cell activation experiments, neogenin-mediated axon guidance models, and tumor microenvironment studies where RGMB expression has been linked to immune cell regulation.

The 100 µl vial format provides sufficient reagent for multiple blotting experiments, and the sodium azide preservative permits convenient refrigerated storage. Aliquot if extended or repeated freeze-thaw cycles are anticipated.