Anti-RFC4 Antibody

Targeting Replication Factor C subunit 4, this rabbit polyclonal Primary Antibody from Antibodies.com is supplied as 100 µl of unconjugated antisera at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol. RFC4 is a core component of the RFC clamp-loader complex that loads PCNA onto primed DNA during replication and repair, making this reagent a useful marker in studies of DNA replication, genome stability, and the DNA damage response. The antibody is validated for Western blot, Immunohistochemistry, and Immunofluorescence workflows across Human, Mouse, and Rat samples. The glycerol-containing buffer permits short-term refrigerated storage, and aliquoting on receipt avoids repeated freeze-thaw cycles that can erode polyclonal titers. Researchers commonly deploy RFC4 immunostaining as a functional readout of clamp-loading activity and as a proliferation-associated marker in cell-based assays.