Anti-Ret (phospho-Y1062) Antibody

Primary antibody from Antibodies.com raised in rabbit against the receptor tyrosine kinase Ret, specifically recognizing the phosphorylated tyrosine residue at position 1062. This polyclonal reagent is supplied as 100 µl of unconjugated IgG at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, validated for western blot and immunohistochemistry workflows on human, mouse, and rat samples. The Y1062 phosphosite sits within an intracellular docking domain that couples Ret to downstream RAS/MAPK and PI3K/AKT signaling cascades following GDNF-family ligand engagement, so this reagent is widely used to probe neuronal crest-derived lineages, enteric nervous system development, kidney morphogenesis, and oncogenic Ret signaling in medullary thyroid carcinoma and other RET-driven tumors. Store the vial at -20 °C in working aliquots to limit freeze-thaw cycles and protect from light during handling. Each lot is validated for phospho-specific recognition in immunoblot and chromogenic tissue staining applications, supporting research use only studies of receptor activation, downstream adaptor recruitment, and disease-associated Ret hyperphosphorylation.