Anti-RENBP Antibody

This rabbit polyclonal reagent from Antibodies.com targets human renin-binding protein, also known as N-acylglucosamine 2-epimerase. The unconjugated IgG antibody is supplied as 100 µl of ready-to-use liquid and is validated for Western blot detection of the RENBP target in human samples. RENBP is encoded on the X chromosome and is expressed in tissues such as the kidney, liver, and adrenal cortex, where it participates in renin sequestration as well as the epimerization step that interconverts N-acylglucosamine and N-acetylmannosamine, a key reaction in sialic acid biosynthesis. The polyclonal antibody recognizes multiple epitopes on the RENBP protein, which migrates at approximately 48 kDa in SDS-PAGE gels, allowing robust signal in western blot workflows using HRP-conjugated secondary antibodies and chemiluminescent or colorimetric substrates. Researchers studying the renin-angiotensin system, sialic acid metabolism, hypertension mechanisms, or X-linked metabolic disorders can use this antibody to probe endogenous RENBP expression in cell lysates and tissue homogenates. For best results, store the vial refrigerated in single-use aliquots to preserve activity across multiple experiments and to avoid repeated freeze-thaw cycles that can degrade antibody performance. For research use only.