Anti-RELA (phospho T435) Antibody

This rabbit polyclonal IgG antibody from Antibodies.com specifically recognizes RELA (NF-κB p65) when phosphorylated at threonine 435. Raised in rabbit and supplied unconjugated in a 50 µl volume, it is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples. The phospho-T435 epitope marks a regulatory modification that researchers monitor as a readout of NF-κB pathway activation. Investigators apply this reagent to cell culture lysates and tissue sections, distinguishing the phosphorylated pool from total RELA to characterize stimulus-dependent signaling. The polyclonal format offers affinity for the modified residue while tolerating variation in neighboring sequence context, supporting reproducible detection across experimental conditions.