Anti-RCC1 Antibody

This polyclonal reagent from Antibodies.com targets RCC1, the chromatin-associated guanine nucleotide exchange factor that loads Ran-GTP and drives nucleocytoplasmic transport, mitotic spindle assembly, and nuclear envelope reassembly. Raised in rabbit, the unconjugated antibody preparation is validated for Western blot (WB) and immunohistochemistry (IHC) on human samples, supporting studies of cell cycle progression, chromosome condensation, and nuclear import pathways. Each vial contains 100 µl of antibody supplied as a liquid aliquot for immunostaining of fixed tissue sections and standard immunoblotting workflows. Researchers commonly apply this reagent to probe RCC1 chromatin binding, investigate Ran-GTPase signaling, and characterize mitotic phenotypes in transformed cell lines. Refrigerate upon receipt, aliquot to limit freeze-thaw cycles, and protect from light to preserve binding activity. For research use only.