Anti-RCAN1 Antibody - Identical to Abcam (ab185931)

RCAN1 (Regulator of Calcineurin 1), a 38 kDa intracellular regulator of calcineurin–NFAT signaling encoded within the Down syndrome critical region of chromosome 21, is the target recognized by this unconjugated rabbit polyclonal IgG from Antibodies.com.

Provided as a 200 µl vial, the antibody is used in western blot, immunofluorescence, and immunohistochemistry workflows and reacts with both human and mouse samples, supporting cross-species studies of calcineurin pathway activity in fixed cells and tissue sections.

Standard protocols include paraformaldehyde fixation for IF and IHC, RIPA-based lysis for WB, and blocking in normal serum to minimize non-specific binding in endogenous expression studies of cardiac hypertrophy, oxidative stress, and neurodegenerative disease models.