Anti-RBM39 Antibody

Produced in rabbit and affinity purified against RBM39 (RNA Binding Motif Protein 39), this unconjugated polyclonal IgG reagent from Antibodies.com recognizes the human target for Western blot applications. RBM39 is a nuclear RNA-binding protein featuring RNA recognition motifs that participates in pre-mRNA splicing, alternative splice site selection, and transcriptional regulation through interactions with the aryl hydrocarbon receptor and other nuclear factors. It has emerged as a therapeutic liability in acute myeloid leukemia and other malignancies, where molecular glue degraders such as indisulam promote its selective ubiquitination and degradation. Each vial is supplied as 200 µl of liquid antibody for immunoblotting of cell lysates and tissue extracts in research use only studies of spliceosome function, transcription-coupled processes, and DNA damage response pathways.