Anti-RBM39 Antibody

RBM39 is an RNA-binding protein that participates in pre-mRNA splicing and transcriptional regulation, and it has attracted considerable interest as a substrate of the E3 ligase DCAF15 that is targeted by aryl sulfonamide drugs such as indisulam. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against RBM39 and recognizes the human protein, making it suitable for Western blot detection of endogenous RBM39 levels in cell lysates and recombinant expression systems. The antibody is supplied in a 100 µl volume, ready for use in standard immunoblotting workflows after dilution in blocking buffer. As a polyclonal reagent, it can recognize multiple epitopes along the RBM39 sequence, which is helpful when probing splice isoforms or co-translational modification states. Researchers studying splicing factor biology, the cellular response to molecular glue degraders, or RBM39-dependent transcriptional programs in cancer and immune cells will find this reagent a practical tool for validating expression levels and degradation phenotypes in vitro.