Anti-RBM15 Antibody

Antibodies.com offers this rabbit polyclonal antibody targeting RBM15 (RNA Binding Motif Protein 15), a key component of the N6-methyladenosine (m6A) RNA methyltransferase complex that works alongside WTAP and METTL3 to install m6A marks on nascent transcripts. RBM15 is also notable for its involvement in the RBM15-MKL1 fusion oncogene characteristic of infant acute megakaryoblastic leukemia with the t(1;22) translocation.

This unconjugated primary antibody, supplied as 100 µl of polyclonal serum raised in rabbit, supports Western blot and immunofluorescence workflows against human samples. Researchers studying m6A epitranscriptomics, RNA splicing regulation, X-chromosome inactivation, or megakaryocyte differentiation use it to probe RBM15 expression and subcellular localization in cell lines and primary tissue. The polyclonal format provides multi-epitope coverage, which can be valuable for detecting full-length RBM15 as well as isoforms relevant to leukemia research and RNA modification studies.