Anti-RBBP6 Antibody

This Rabbit polyclonal antibody from Antibodies.com specifically targets RBBP6 (Retinoblastoma-Binding Protein 6), a multifunctional nuclear protein implicated in mRNA 3'-end processing, cell-cycle checkpoint control, and p53-mediated apoptosis. The reagent is supplied as an unconjugated preparation at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, packaged in a 100 µl vial suitable for multiple western blot experiments.

Validated for western blot detection across human, mouse, and rat samples, the antibody enables researchers to examine endogenous RBBP6 expression in cell lysates and tissue homogenates. RBBP6 contributes to polyadenylation complex assembly and has been linked to cancer biology through its interaction with p53 and Rb tumour suppressor pathways, making it relevant to studies of proliferation, DNA damage response, and tumourigenesis. The polyclonal format offers recognition of multiple epitopes on the RBBP6 protein, which can be advantageous when probing truncated isoforms or post-translationally modified variants.

Storage recommendations are 4 °C short term; for longer stability, aliquot and store at -20 °C and avoid repeated freeze-thaw cycles. The buffer contains 0.05% sodium azide as a preservative; handle with appropriate laboratory precautions. Intended for research use only and not for diagnostic or therapeutic applications.