Anti-RBBP5 Antibody

RBBP5 (Retinoblastoma-Binding Protein 5) is a core scaffolding subunit of the MLL/SET1 (COMPASS-like) histone H3 lysine 4 methyltransferase complex that supports chromatin modification and transcriptional activation at target loci. This unconjugated rabbit polyclonal primary antibody from Antibodies.com is raised against the human RBBP5 protein and is supplied at 200 µl per vial for use in Western blot and immunofluorescence workflows, with cross-reactivity to Mouse orthologs confirmed in validation.

Its polyclonal IgG format provides multi-epitope recognition of endogenous RBBP5 (~56 kDa) by immunoblotting and supports nuclear localization studies by immunofluorescence across cultured cell lines and tissue sections. The unconjugated IgG isotype pairs with standard secondary detection reagents, accommodating chemiluminescent, fluorescent, or chromogenic assays. For long-term storage, aliquot the vial contents and freeze, protected from light; avoid repeated freeze-thaw cycles to preserve antibody activity.

Intended for research use only, the reagent supports studies of epigenetic regulation, histone H3K4 methylation, MLL-rearranged leukemia biology, and hematopoietic development where RBBP5 is of mechanistic interest.