Anti-RBBP5 Antibody

Retinoblastoma-binding protein 5 (RBBP5) is a WD40-repeat scaffold component of MLL/SET1 COMPASS-like histone H3 lysine 4 methyltransferase complexes that drive chromatin-based transcription control, and this Antibodies.com primary antibody supplies a polyclonal rabbit reagent for tracking that target across western blot and immunofluorescence workflows on human and mouse samples. Each vial delivers 100 µl of unconjugated IgG, formatted for direct use with secondary antibody detection chemistries such as HRP, Alexa Fluor, or DyLight conjugates depending on the chosen application.

Investigators probing epigenetic writers, MLL-rearranged leukemia biology, or histone methylation dynamics use RBBP5 immunoblots to confirm complex integrity, and IF imaging to localize the protein to nuclear compartments during differentiation, cell cycle progression, and stress responses. Endogenous detection in whole-cell lysates and fixed-cell preparations yields reproducible banding at the expected molecular weight, and the polyclonal format broadens epitope coverage to support work on truncated isoforms or post-translationally modified forms of RBBP5 in chromatin and transcription studies.