Anti-Rb (phospho-S807) Antibody

Phosphorylation-specific detection of the retinoblastoma tumor suppressor protein at serine 807 is enabled by this recombinant rabbit monoclonal reagent. The antibody recognizes a synthetic phosphopeptide corresponding to the S807 site, a residue phosphorylated by CDK complexes during G1/S transition, which releases E2F transcription factors and drives commitment to DNA synthesis. Researchers apply it to monitor pathway activation in synchronized cell populations, small-molecule inhibitor-treated samples, and tumor-derived material where cell cycle re-entry is being interrogated. Its unconjugated format accepts user-selected secondary reagents and supports western blot, immunocytochemistry, immunofluorescence, and immunohistochemistry workflows performed on both cultured cells and tissue sections. Reactivity has been confirmed against human, mouse, and rat samples, making the reagent practical across standard laboratory model systems. The product ships as a 100 µl aliquot in 1*TBS (pH7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative, supplied by Antibodies.com as a recombinant preparation intended for research use only. Store refrigerated; protect from light and limit freeze-thaw cycles to preserve phospho-epitope binding activity.