Anti-Rb Antibody

Manufactured by Antibodies.com, this rabbit polyclonal antibody targets the retinoblastoma-associated protein (Rb), also known by its synonyms p105-Rb, p110-RB1, pp110, pRb, and RB1. The immunogen is a synthesized peptide derived from human Rb around the non-phosphorylation site of serine 811, and the reagent detects endogenous levels of Rb protein in human, mouse, and rat samples. Supplied as an unconjugated polyclonal antibody raised in rabbit and affinity-purified by affinity-chromatography using the epitope-specific immunogen, the product is provided in a 50 µl liquid format at a concentration of 1 mg/mL, formulated in PBS containing 50% glycerol, 0.5% BSA, and 0.02% sodium azide. Validated applications include Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry/Immunofluorescence (ICC/IF), and ELISA, making the reagent suitable for a broad range of cell and tissue analyses. For handling, the vial is shipped at 4°C; upon delivery it should be aliquoted and stored at -20°C, with repeated freeze/thaw cycles avoided to preserve antibody activity. Intended for research use only, this polyclonal reagent from Antibodies.com offers a reliable option for laboratories studying Rb pathway signaling, tumor suppressor biology, and cell-cycle regulation across multiple model systems.