Anti-Rb (Ab-807) Antibody

The retinoblastoma (Rb) tumor suppressor is a 110 kDa nuclear phosphoprotein that restrains E2F transcription factors and gates the G1 to S phase transition of the cell cycle. This rabbit polyclonal reagent from Antibodies.com was raised against a synthetic peptide spanning the Ab-807 epitope region of Rb and is supplied unconjugated at 100 µl per vial, ready to dilute into standard Western blot and immunohistochemistry workflows.

Validated for WB and IHC on human, mouse, and rat samples, the antibody supports detection of endogenous Rb across proliferating and quiescent cell populations, tumor versus normal tissue comparisons, and studies of cell cycle exit and re-entry following growth factor withdrawal or pharmacological arrest. Aliquot the polyclonal stock on arrival and store at -20 °C in working volumes to limit freeze-thaw cycles of the antiserum.