Anti-RASH / RASK / RASN Antibody

The Antibodies.com rabbit polyclonal reagent targets a shared epitope on the Ras family of small GTPases, recognizing the HRAS, KRAS, and NRAS isoforms whose catalytic G-domains share highly conserved switch regions and P-loop residues. Raised in rabbits and supplied as an unconjugated antiserum at 100 µl per vial, the antibody is validated for western blot and immunohistochemistry workflows on human samples, supporting studies of MAPK and PI3K effector pathway activation in tumor lysates and formalin-fixed tissue sections. The polyclonal format increases the chance of capturing isoform-specific post-translational modifications and membrane-localized, GTP-loaded Ras variants that drive proliferation in colorectal, pancreatic, and non-small-cell lung cancer models. Researchers investigating mutation-independent Ras activation, wild-type Ras biology, or effector binding will find the unconjugated formulation compatible with both HRP- and fluorophore-conjugated secondary reagents.