Anti-RAPGEF3 Antibody

Offered by Antibodies.com, this affinity-purified rabbit polyclonal reagent recognizes endogenous levels of RAPGEF3 (also known as EPAC1, cAMP-GEFI, CGEF1 and EPAC), a ~99 kDa guanine nucleotide exchange factor implicated in cAMP-mediated activation of Rap1. The antibody is supplied as a 50 µl liquid aliquot at approximately 1 mg/ml in phosphate-buffered saline (PBS, pH 7.2) containing 0.05% sodium azide as preservative, and is unconjugated, allowing users to pair it with their own detection chemistries. The host species is Rabbit, the clonality is Polyclonal, and purity is reported as greater than 95% by SDS-PAGE following affinity chromatography against an epitope-specific immunogen derived from recombinant full-length human RAPGEF3. Validated applications include Western blot (WB), Immunohistochemistry (IHC) and Immunofluorescence (IF), and the reagent has been verified to react with Human, Mouse and Rat samples, making it a versatile choice for cross-species signaling and cAMP/Epac1 pathway studies. For handling, the manufacturer recommends short-term storage at 4 °C after arrival with aliquoting and long-term storage at -20 °C, while avoiding repeated freeze/thaw cycles to preserve activity. This product is intended for research use only and is not approved for diagnostic or therapeutic applications.