Anti-RAPGEF3 Antibody

RAPGEF3, also known as EPAC1 (exchange protein directly activated by cAMP 1), is a cAMP-regulated guanine nucleotide exchange factor that activates Rap1 and Rap2 small GTPases and mediates protein kinase A-independent cAMP signaling in a range of cell types. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against RAPGEF3 and shows reactivity with human, mouse, and rat samples, supporting cross-species studies in cell signaling, vascular biology, and cardiovascular research.

Each vial contains 100 µl of polyclonal antibody formulated at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2. The unconjugated format allows flexible pairing with user-selected secondary detection reagents, and the reagent has been validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows in cell lysates, fixed tissue sections, and cultured cell preparations. Protect from light and aliquot to limit repeated freeze-thaw cycles. Intended for research use only.