Anti-RAMP1 Antibody

Offered by Antibodies.com through AFMS, this affinity-purified reagent is a rabbit polyclonal antibody raised against receptor activity-modifying protein 1 (RAMP1), the single-pass type I transmembrane accessory protein that partners with calcitonin-receptor-like receptor (CRLR/CALCRL) to generate the CGRP receptor and with the calcitonin receptor to form an amylin-responsive complex. Supplied as 50 µl of an unconjugated, IgG-based polyclonal preparation at approximately 1 mg/ml in phosphate-buffered saline (PBS) at roughly pH 7.2 with 15 mM sodium azide as preservative, the antibody is validated for Western blot (WB) detection of endogenous RAMP1 in human, mouse and rat samples. Recommended for researchers investigating GPCR trafficking, CGRP/amylin signaling, vascular and neuronal RAMP1 biology, and related receptor activity-modifying protein pathways. Shipped cold for short-term stability; for long-term storage, aliquot and keep at −20 °C, avoiding repeated freeze/thaw cycles to preserve antibody activity. Each lot is supplied with detailed application notes and technical support from Antibodies.com.