Anti-RALB Antibody

RalB is a small Ras-related GTPase that participates in exocyst-driven vesicle trafficking, autophagosome biogenesis, and signaling cascades downstream of active Ras. The unconjugated polyclonal reagent from Antibodies.com is raised in rabbit and detects RalB in human, mouse, and rat samples, with verified use in Western blot and immunohistochemistry workflows.

Each vial contains 100 µl at 1 mg/ml, prepared in PBS with 0.1% sodium azide and 50% glycerol to keep the protein stable during routine handling. The azide concentration protects against microbial contamination on the bench, and the glycerol cryoprotectant lets the antibody survive occasional freeze-thaw cycles when stored at -20°C between uses. Short-term storage at 4°C is convenient for active projects.

Because the antibody is polyclonal, it recognizes multiple epitopes across the RalB sequence, which helps when the target is partially degraded in lysates or masked in fixed tissue sections. Researchers investigating RalB-dependent secretion, Toll-like receptor signaling, and tumor survival pathways use this reagent to probe both membrane-bound and cytosolic pools of the GTPase.