Anti-RAG2 Antibody

RAG2 (Recombination Activating Gene 2) functions as a critical component of the RAG1/RAG2 recombinase complex that initiates V(D)J recombination, the somatic rearrangement process that assembles variable region exons of immunoglobulin and T cell receptor genes. This polyclonal reagent targets RAG2 for detection across human, mouse, and rat samples in western blot, immunohistochemistry, and immunofluorescence workflows.

Produced in rabbit and supplied as an unconjugated 100 µl aliquot, this primary antibody from Antibodies.com supports studies of lymphocyte development, immunodeficiency research including SCID and Omenn syndrome models, and investigation of DNA cleavage events at recombination signal sequences. The unconjugated format provides flexibility in downstream secondary antibody selection and detection chemistry.

Research applications include characterizing RAG2 expression patterns in thymus, bone marrow, and lymphoid tissues, mapping subcellular localization of the recombinase complex, and probing protein levels in knockout or mutant models used to dissect the non-homologous end joining pathway.