Anti-Rag A / B Antibody

This polyclonal antibody from Antibodies.com targets Rag A and Rag B, two related Ras-family GTPases that operate as heterodimers to relay amino acid availability to the mTORC1 complex and control cell growth. Raised in rabbit, the reagent is supplied unconjugated in a 100 µl vial and validated across western blot, immunohistochemistry, and ELISA workflows on human, mouse, and rat samples. Researchers investigating nutrient sensing, autophagy regulation, and growth signaling rely on Rag GTPase antibodies to map how cells interpret leucine, glutamine, and other amino acid cues that drive mTOR recruitment to the lysosomal surface. As a polyclonal reagent, it binds multiple epitopes on the Rag A/B proteins, giving broader recognition than a monoclonal clone and supporting surveys of Rag expression across tissue panels and lysate screens. The unconjugated format lets researchers couple the antibody to fluorophores, biotin, or HRP depending on the detection chemistry their protocol requires, and it is appropriate for both research use only and in vitro studies of mTOR pathway activation.