Anti-Raf-B Antibody

This Rabbit polyclonal antibody targets Raf-B (BRAF), a serine/threonine-protein kinase that sits upstream of the MAPK/ERK cascade and is widely investigated for its role in oncogenic signaling. The unconjugated reagent is supplied by Antibodies.com as 100 µl of liquid antibody raised in Rabbit and validated for Western blot, immunohistochemistry, and ELISA workflows against Human, Mouse, and Rat samples. Researchers commonly apply it to probe BRAF expression in melanoma, colorectal, and thyroid carcinoma models, where activating mutations such as V600E drive constitutive pathway activation. The polyclonal format recognizes multiple epitopes on the target, supporting reliable detection across tissue sections and Western blots. For best results, store frozen at -20°C in single-use aliquots, protect from light, and limit freeze-thaw cycles to preserve antibody activity through longitudinal signaling studies.