Anti-Raf-B Antibody

Produced in rabbit hosts by Antibodies.com, this polyclonal unconjugated reagent targets the Raf-B serine/threonine kinase (also known as BRAF), a central node in the RAF/MEK/ERK signalling cascade that drives proliferation, differentiation, and survival programmes in many cell types. Validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, the antibody recognises both human and mouse Raf-B, supporting comparative studies in tumour cell lines, primary tissue sections, and xenograft-derived samples. Each vial contains 100 µL of ready-to-use reagent suited to multiple staining and blotting experiments, and the polyclonal nature of the preparation allows recognition of multiple epitopes across the target protein, useful when probing phosphorylation-dependent or isoform-specific variants. Researchers investigating melanoma, thyroid, colorectal, and hairy cell leukaemia biology, where activating mutations in BRAF are frequent, rely on this reagent to map pathway activity, confirm knockout efficiency, and validate upstream signalling events alongside MEK and ERK readouts.