Anti-RAD17 Antibody

This unconjugated primary antibody from Antibodies.com targets RAD17, a key regulator of the DNA damage checkpoint that loads the 9-1-1 (RAD9-RAD1-HUS1) clamp onto stalled replication forks and supports ATR-mediated signaling. Raised in rabbit and purified as a polyclonal reagent, the antibody recognizes the human RAD17 protein and cross-reacts with mouse and rat orthologs, making it well suited to comparative studies across standard laboratory models.

Validated for western blot and immunohistochemistry, the reagent is supplied as a 100 µl liquid aliquot and is unconjugated, allowing researchers to pair it with secondary antibodies and detection chemistries of their choice. It is intended for research use only and is commonly used to monitor checkpoint activation, replication stress, and genotoxic responses in cultured cell lines and tissue sections.