Anti-RAC2 Antibody

RAC2 is a 21 kDa member of the Rho family of small GTPases, predominantly expressed in cells of hematopoietic lineage where it regulates actin cytoskeleton reorganization, NADPH oxidase assembly, and downstream kinase cascades linked to cell adhesion and migration. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against RAC2 and validated for Western blot detection of endogenous protein in human, mouse, and rat lysates.

The antibody is supplied as 50 µl of liquid stock at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, allowing convenient storage and aliquoting for repeated use. The polyclonal format offers broad epitope coverage, which can be useful when probing conformational variants or when phospho-state-independent recognition is desired across experimental conditions.

Typical research applications include studies of neutrophil respiratory burst, leukocyte chemotaxis, hematopoietic stem cell signaling, and characterization of RAC2 mutations associated with severe combined immunodeficiency and other phagocyte disorders. The reagent is intended for research use only and is not validated for diagnostic or therapeutic procedures.