Anti-RAC1 Antibody

RAC1 sits at a regulatory nexus in cell signaling, and this Rabbit polyclonal IgG reagent from Antibodies.com gives researchers a specific tool to track the protein across multiple model systems. The antibody recognizes a 21 kDa member of the Rho family of small GTPases, capturing both the inactive GDP-bound pool and the active GTP-bound conformation in cell lysates and fixed specimens. The unconjugated format lets each lab pair the primary reagent with a labeled secondary of their own choosing, supporting either chromogenic or fluorescent readout strategies.

Validated applications include Western blot and immunofluorescence across Human, Mouse, and Rat samples, covering studies of cytoskeletal remodeling, lamellipodia and membrane ruffle assembly, focal complex turnover, growth factor-driven migration, NADPH oxidase assembly, and invasion-related pathways relevant to cancer, cardiovascular, and neurobiology research. The reagent is supplied as 100 µl of polyclonal IgG per vial, with storage at -20 °C in working aliquots recommended to limit freeze-thaw degradation, and protection from light during any subsequent conjugated secondary detection step.