Anti-RABEP1 Antibody

This unconjugated rabbit polyclonal IgG reagent from Antibodies.com targets RABEP1 (Rab GTPase-binding effector protein 1), a key endosomal trafficking regulator. Supplied as a 200 µl polyclonal antibody aliquot, it is validated for western blot detection of RABEP1 in mouse tissue and cell lysates for research applications.

RABEP1, also called Rabaptin-5, acts as a downstream effector of Rab5 GTPase and coordinates early endosome fusion, receptor recycling, and cargo sorting along the endolysosomal pathway. Researchers investigating membrane trafficking, signal-dependent receptor internalization, and vesicle tethering use this reagent to characterize RABEP1 expression, study complex assembly with Rab5, and explore its role in neurodegenerative disease models such as Huntington's disease, where RABEP1 is reported to interact with HAP1.

Provided as a 200 µl liquid vial of unconjugated IgG, the reagent should be refrigerated, kept away from light, and protected from repeated freeze-thaw cycles to preserve antibody activity. Intended for research use only, it is reactive with mouse samples and applicable to standard western blot protocols.