Anti-RAB5C Antibody

This polyclonal antibody recognizes RAB5C, a Rab family small GTPase that regulates early endosome biogenesis, homotypic endosome fusion, and vesicular trafficking along the endocytic pathway. Supplied by Antibodies.com at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the reagent ships in a 100 µl vial that supports multiple experimental runs.

Validated for Western blot (WB) and immunohistochemistry (IHC), the unconjugated reagent shows reactivity with Human, Mouse, and Rat samples, allowing comparative studies across common model systems. Endogenous RAB5C can be detected in cell lysates for expression-level work and in fixed tissue sections for spatial localization studies, supporting research into receptor internalization, cargo sorting, and endosomal signaling cascades.

The 50% glycerol cryoprotectant combined with the 1 mg/ml stock concentration permits storage at -20 °C with minimal freeze-thaw degradation, while the 0.1% sodium azide preservative guards against microbial contamination during routine bench handling. Aliquoting on first use is recommended to preserve antibody activity over long-term storage.