Anti-RAB5A Antibody

A recombinant rabbit monoclonal antibody from Antibodies.com that selectively binds RAB5A, a small Ras-related GTPase governing early endosome biogenesis, endocytic vesicle fusion, and receptor trafficking through the endosomal system. Supplied unconjugated in a 100 µl vial of TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative, the reagent is validated for western blot and immunohistochemistry across human, mouse, and rat samples. Researchers use it to map early endosome subcellular localization, follow transferrin and EGF receptor internalization, profile RAB5A activity in cancer models, and dissect signalling events coordinated by the RAB5 effector machinery, including EEA1 and Rabaptin-5 recruitment. The recombinant clonality delivers batch-to-batch reproducibility for detection of endogenous RAB5A in cell lysates and fixed tissue sections. Store refrigerated; avoid repeated freeze-thaw cycles to preserve binding activity.