Anti-RAB4A Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com specifically recognizes RAB4A, a small Ras-related GTPase that localizes to early endosomes and drives receptor recycling, cargo sorting, and vesicular transport along the endocytic pathway. The reagent is raised in rabbit and supplied as a 100 µL liquid aliquot in a vial, suitable for Western blot and immunofluorescence workflows on human, mouse, and rat samples. Because the target is unconjugated, it can be paired with a secondary reporter of choice for multiplex labeling or for chromogenic detection after immunoblotting.

RAB4A is widely studied in the context of membrane trafficking biology, including GLUT4 translocation, transferrin receptor recycling, and the early-endosome-to-recycling-endosome pathway. Published work has linked altered RAB4A expression to several cancer models, including breast and hepatocellular carcinoma, and to autophagy regulation, making this primary antibody useful for researchers probing endocytic flux, receptor turnover, and small-GTPase signaling. The polyclonal format provides multi-epitope recognition, which can be advantageous when detecting endogenous RAB4A across different sample preparations and post-translational states.