Anti-Rab4A Antibody

Rab4A is a small GTPase of the Rab family that orchestrates receptor recycling through early endosomes, directing cargo from sorting endosomes back to the plasma membrane. It controls the surface abundance of nutrient transporters and signaling receptors, including EGFR and the transferrin receptor, and is implicated in GLUT4 trafficking, synaptic vesicle recycling, and the entry pathway of several viruses. Researchers studying membrane trafficking dynamics in neurons, adipocytes, and immune cells rely on well-validated Rab4A reagents to map these routes.

This recombinant rabbit monoclonal reagent from Antibodies.com is raised against Rab4A and supplied as 50 µl of unconjugated antibody in a single-use vial, formulated in TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative. It is validated for western blot (WB) and immunocytochemistry/immunofluorescence (ICC/IF), and it cross-reacts with Human, Mouse, and Rat samples, supporting comparative studies across human cell lines and rodent primary cultures. Store aliquots frozen; protect from light and avoid repeated freeze-thaw cycles to preserve activity.