Anti-RAB31 Antibody

The RAB31 GTPase, a member of the Ras-related small GTPase superfamily, localizes predominantly to the trans-Golgi network and late endosomal compartments, where it coordinates vesicular trafficking, cargo sorting, and receptor recycling between endocytic and secretory pathways. This polyclonal antibody from Antibodies.com was raised in rabbit and is supplied at 1 mg/ml in phosphate-buffered saline (PBS) with 0.05% sodium azide, adjusted to approximately pH 7.2.

Validated for western blot (WB) and immunocytochemistry (ICC) workflows, the reagent recognizes endogenous RAB31 in human, mouse, and rat samples, supporting comparative trafficking studies across standard mammalian model systems. RAB31 is a useful marker for researchers examining melanosome transport in melanocytes, EGFR routing in epithelial cancers, and phagocytic cup closure in macrophages, as well as Golgi-associated secretory pathway activity in cell biology and oncology settings.

The 50 µl aliquot provides sufficient material for multiple membrane and cytospin preparations, and the unconjugated format lets users pair it with their preferred secondary reagents, from HRP and Alexa Fluor dyes to other fluorophores, depending on whether the downstream readout is chemiluminescent or fluorescence-based.