Anti-RAB27A Antibody

The Antibodies.com Anti-RAB27A polyclonal antibody is a rabbit-derived research reagent raised against the RAB27A small GTPase, a key regulator of vesicle docking and regulated exocytosis in melanocytes, cytotoxic T lymphocytes, NK cells, and pancreatic beta cells. Supplied as an unconjugated, 100 µl vial, it is validated for Western blot (WB) and immunohistochemistry (IHC) workflows and shows reactivity with human, mouse, and rat samples, supporting studies of melanosome transport, granule secretion, and the molecular basis of Griscelli syndrome type 2, which is caused by loss-of-function mutations in RAB27A. The polyclonal reagent recognizes a member of the Rab family of trafficking GTPases that mediates peripheral vesicle anchoring and interaction with downstream effectors such as melanophilin and myosin-Va, supporting investigations in cell biology, immunology, and pigmentation research.