Anti-RAB27A Antibody

This polyclonal antibody targets RAB27A, a small Rab-family GTPase that controls vesicle docking and trafficking in secretory lysosomes. It is raised in rabbit and supplied by Antibodies.com as a 100 µl vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant.

Validated for Western blot (WB) and immunohistochemistry (IHC) workflows, the reagent shows reactivity with Human, Mouse, and Rat samples and is supplied unconjugated, with no reporter attached. Researchers studying cytotoxic granule release in NK cells and CD8+ T lymphocytes, melanosome transport in melanocytes, platelet dense-granule biogenesis, and the molecular pathology of Griscelli syndrome type 2 routinely use this reagent in their investigations.

RAB27A coordinates membrane trafficking through effector proteins such as melanophilin (MLPH), myosin Va, and Munc13-4, making the antibody useful for assays of immune synapse formation, lytic granule secretion, and pigmentation biology. Store the vial refrigerated at 4 °C for short-term use, or freeze in single-use aliquots for long-term storage; protect from light and minimize freeze-thaw cycles to preserve activity.