Anti-RAB14 Antibody

RAB14 is a member of the Rab family of Ras-related small GTPases that regulates intracellular membrane trafficking, particularly between the Golgi apparatus and early endosomes. This rabbit polyclonal primary antibody from Antibodies.com is raised against RAB14 and supplied as an unconjugated reagent at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, in a 100 µl vial.

Published research has linked RAB14 function to phagosome maturation in macrophages, hepatitis C virus replication, autophagy regulation, and the biogenesis of Salmonella-containing vacuoles. These roles make RAB14 a target of active interest in cell biology, host-pathogen interaction studies, and vesicular transport research.

The antibody is validated for Western blot (WB) applications and shows reactivity against human, mouse, and rat samples, supporting cross-species comparative work. Because it is unconjugated and polyclonal, the reagent offers flexibility in downstream detection, including compatibility with HRP- or fluorophore-conjugated secondary antibodies, and recognizes multiple epitopes on the target protein in denatured samples.

For handling, the antibody should be stored refrigerated to preserve activity, with aliquoting recommended to limit freeze-thaw cycles. The 1 mg/ml formulation supports convenient dilution into standard western blot workflows. Researchers studying membrane trafficking dynamics, intracellular transport, innate immunity, and related cellular signaling pathways can integrate this reagent into immunoblotting experiments.