Anti-Rab 6A Antibody

Raised in rabbit and supplied as an unconjugated polyclonal reagent from Antibodies.com, this antibody recognizes Rab6A, a member of the Rab family of small GTPases that orchestrates retrograde membrane trafficking from the Golgi apparatus to the endoplasmic reticulum. Rab6A also participates in Golgi ribbon maintenance, cytokinesis, and the spatial positioning of organelles, making it a useful marker in cell biology studies of vesicular transport and secretory pathway dynamics.

The reagent reacts with the human, mouse, and rat orthologues, supporting translational workflows that span patient-derived samples, rodent disease models, and comparative controls. It is validated for western blot, immunohistochemistry, and ELISA, accommodating both qualitative imaging of tissue sections and quantitative readouts of protein expression across whole-cell lysates. The antibody is provided in a 100 µl volume as an unconjugated IgG preparation, which can be paired with secondary antibodies conjugated to fluorescent dyes, enzymes, or biotin for flexible assay design.

Research uses include profiling Golgi morphology, investigating trafficking defects linked to neurodegenerative disease, and dissecting host-pathogen interactions where Rab6A-dependent pathways are co-opted by viruses. Standard antibody handling guidance applies, and aliquoting is recommended to limit freeze-thaw cycles.