Anti-QRSL1 Antibody

The QRSL1 protein, also called glutaminyl-tRNA synthase-like 1, forms part of the mitochondrial glutamyl-tRNA amidotransferase (GatCAB) complex that performs the indirect transamidation pathway, converting mischarged Glu-tRNA(Gln) to correctly amidated Gln-tRNA(Gln) for organellar translation. This rabbit polyclonal reagent from Antibodies.com is supplied as an unconjugated IgG in a 200 µL vial, raised against the QRSL1 target and validated for Western blot detection in human and mouse samples. It supports research into mitochondrial aminoacyl-tRNA biosynthesis, the transamidation route that supplements direct glutaminyl-tRNA charging in mammalian mitochondria, and broader organellar translation studies. Provided as a ready-to-titrate liquid, the antibody integrates into standard SDS-PAGE and immunoblotting workflows and pairs with HRP-conjugated secondary reagents for chemiluminescent readouts of mitochondrial lysates and tissue homogenates. Storage at refrigerated 4 °C in aliquoted form preserves activity for repeated use, with freeze-thaw cycles kept to a minimum for working stocks.