Anti-QPCT Antibody

This polyclonal rabbit antibody targets human QPCT (glutaminyl-peptide cyclotransferase), provided by Antibodies.com as an unconjugated primary reagent in a 100 µl liquid format. QPCT catalyzes the conversion of N-terminal glutamine residues into pyroglutamate, a post-translational modification linked to amyloid-beta maturation, neuroinflammatory signaling, and tumor cell biology. The antibody is validated for Western blot (WB) and immunofluorescence (IF) applications on human samples, supporting studies of neuropeptide processing, enzyme regulation, and disease mechanism research. Shipped as a ready-to-dilute liquid, the reagent should be stored at -20 °C and divided into single-use aliquots to limit freeze-thaw cycles and preserve binding activity over time. Investigators examining Alzheimer's disease biomarkers, melanoma cell signaling, or neuroendocrine pathway components can use this reagent to detect endogenous QPCT in whole-cell lysates and fixed tissue sections.