Anti-QPCT Antibody

QPCT, or Glutaminyl-peptide cyclotransferase, is an enzyme that catalyzes the formation of N-terminal pyroglutamate residues on peptides and proteins, a post-translational modification implicated in amyloid-beta peptide maturation and broader neurodegenerative disease research. This rabbit polyclonal antibody from Antibodies.com is raised against QPCT and is intended for researchers investigating glutaminyl cyclase activity in human cell and tissue models.

Supplied as 100 µl of unconjugated antibody at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the reagent is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples. The polyclonal format allows recognition of multiple epitopes across the target, which is helpful when working with fixed tissue sections or denatured lysates where single-epitope masking can otherwise compromise signal.

Store refrigerated at 4°C; the 50% glycerol cryoprotectant buffer supports repeated freeze-thaw cycles and routine aliquoting for working stocks. The antibody is intended for in vitro research use only, including studies of QPCT expression, subcellular localization, and enzymatic regulation in the context of Alzheimer's disease and related pathologies.