Anti-QDPR Antibody

QDPR (Quinoid Dihydropteridine Reductase) is a cytosolic enzyme essential for the regeneration of tetrahydrobiopterin (BH4), a cofactor required by phenylalanine hydroxylase and related aromatic amino acid hydroxylases that drive neurotransmitter biosynthesis. This polyclonal antibody from Antibodies.com is raised in rabbit and supplied at 1 mg/ml in PBS buffer containing 0.1% sodium azide and 50% glycerol, delivered as a 100 µl vial volume for use across multiple experiments.

Validated for Western blot (WB) and immunohistochemistry (IHC), the unconjugated reagent reacts with human, mouse, and rat QDPR, supporting comparative work across model systems and patient-derived samples. Researchers investigating BH4 metabolism, hyperphenylalaninemia, and the synthesis of dopamine and serotonin can use this reagent to probe enzyme distribution in neural and peripheral tissues.

The polyclonal format recognizes multiple epitopes on the QDPR target, which can strengthen signal in tissues where expression is low or variable. Storage at -20°C with aliquoting to limit freeze-thaw cycles is recommended to preserve activity for repeated Western blot and immunohistochemistry experiments.