Anti-PYK2 Antibody

Manufactured by Antibodies.com as a primary antibody for research use only, this mouse monoclonal reagent specifically targets PYK2 (also known as PTK2B / protein tyrosine kinase 2 beta), a non-receptor tyrosine kinase involved in integrin signaling, cytoskeletal remodeling, and calcium-induced MAPK activation. The unconjugated antibody is supplied as 50 µl of purified mouse monoclonal in a stabilizing buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% sodium azide, and 50% glycerol, with an estimated purity of greater than 95% as determined by antigen affinity purification. It is validated for Western Blot application on human samples and is intended for use in signal-transduction and cell-adhesion studies where endogenous PYK2 expression is being profiled. Researchers should aliquot and store the antibody according to standard -20 °C short-term / -80 °C long-term conditions to preserve activity, avoiding repeated freeze-thaw cycles. Typical Western Blot working dilutions in the 1:500–1:2000 range yield clean detection of the ~116 kDa PYK2 band in lysates of human origin. Available through the AFMS catalogue, the reagent offers consistent lot-to-lot performance backed by Antibodies.com's quality control and is well suited to laboratories investigating focal adhesion kinase family signaling, neuronal calcium signaling, or related cancer and inflammation pathways.