Anti-Pyk2 (Ab-402) Antibody

This polyclonal reagent from Antibodies.com specifically detects Pyk2 phosphorylated at tyrosine 402, an autophosphorylation site critical for kinase activation within the FAK family signaling network. Pyk2, also known by the gene symbols PTK2B and FAK2, is a non-receptor tyrosine kinase that links calcium signaling to cytoskeletal remodeling, ion channel regulation, and cell migration in neurons, osteoclasts, and immune cells. The antibody is raised in rabbit, purified as an unconjugated polyclonal antiserum, and supplied at 100 µl, ready for western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples. Researchers studying synaptic plasticity, integrin signaling, or vascular smooth muscle responses can probe endogenous phosphorylation levels in cell culture lysates and tissue cryosections, and the reagent is shipped refrigerated for stability. For long-term storage, aliquot and freeze at -20 °C or below, avoiding repeated freeze-thaw cycles to preserve phospho-specific binding activity.