Anti-PYGB Antibody

Primary antibody targeting glycogen phosphorylase brain form (PYGB), a key enzyme in glycogen mobilization within neural tissue. This unconjugated rabbit polyclonal reagent from Antibodies.com is validated for Western blot (WB) and immunofluorescence (IF) workflows, with demonstrated reactivity against Human, Mouse, and Rat samples. Supplied as a 50 µl liquid aliquot, the antibody allows detection of endogenous PYGB in cell and tissue lysates, supporting studies in neurobiology, brain energy metabolism, and glycogen turnover signaling. Researchers use it to investigate astrocytic glycogen metabolism, neural energy homeostasis, and isoform-specific expression patterns distinguishing the brain isoform (PYGB) from the muscle (PYGM) and liver (PYGL) glycogen phosphorylases. Suitable for both standard immunoblotting and fluorescence-based microscopy imaging, the reagent performs reliably in immunofluorescence staining of cultured cells and tissue sections. Store refrigerated and protect from light; avoid repeated freeze-thaw cycles to preserve antibody activity. Provided by Antibodies.com, this polyclonal reagent is intended for research use only and integrates into common laboratory protocols for protein expression analysis across neuroscience, metabolic disease, and glycogen storage research.