Anti-PYCR1 Antibody

Produced by Antibodies.com, this Rabbit polyclonal reagent targets PYCR1 (Pyrroline-5-carboxylate reductase 1), a mitochondrial enzyme that catalyzes the NAD(P)H-dependent reduction of pyrroline-5-carboxylate to proline and plays a central role in cellular proline biosynthesis. The unconjugated antibody is supplied as 100 µl of liquid at 1 mg/ml in PBS containing 0.1% Sodium Azide and 50% glycerol, a formulation supporting routine bench handling and aliquoted frozen storage at -20°C to preserve activity through repeated freeze-thaw cycles.

Validated for Western blot and immunohistochemistry workflows, the reagent binds the PYCR1 target in Human, Mouse, and Rat samples, supporting studies of proline metabolism, mitochondrial biology, and cancer research contexts where PYCR1 dysregulation has been linked to tumor proliferation and connective tissue phenotypes. Polyclonal reactivity across multiple species enables cross-species comparative work and use as a primary antibody in immunostaining of fixed tissue sections and in immunoblotting of cell or tissue lysates.

Each vial is intended for laboratory research use only and is provided as an unconjugated format, allowing researchers to pair it with custom secondary detection reagents, fluorophores, or HRP conjugates as required by their specific Western blot or immunohistochemistry protocol.