Anti-PXN Antibody

This rabbit polyclonal antibody from Antibodies.com recognizes paxillin (PXN), a 68 kDa focal adhesion phosphoprotein that acts as a scaffold at integrin-mediated adhesion sites, recruiting structural and signaling components to the actin cytoskeleton. Validated for Western blot and immunohistochemistry, the reagent detects endogenous paxillin in human, mouse, and rat samples, supporting comparative studies across species and tissue types. The unconjugated antiserum is supplied as 100 µl, allowing flexible pairing with user-selected fluorophore- or HRP-conjugated secondary reagents for immunofluorescence or chromogenic detection workflows. For repeated use, aliquot the reagent and store at -20 degrees C; limiting freeze-thaw cycles preserves antibody titer over time. Investigators working on integrin signaling, focal adhesion turnover, cytoskeletal remodeling, or cell migration can apply this antibody to monitor adhesion complex dynamics in cell lysates and fixed tissue sections.