Anti-PXN Antibody

Manufactured by Antibodies.com, this rabbit polyclonal IgG antibody recognizes paxillin (PXN), a focal adhesion-associated adaptor protein of roughly 68 kDa that links integrin signaling to the actin cytoskeleton. Supplied as an unconjugated 200 µl preparation, the reagent is validated for western blot and immunohistochemistry workflows on human samples, supporting detection of the full-length target in cell lysates and fixed tissue sections. Investigators studying focal adhesion turnover, cytoskeletal remodeling, cell migration, and integrin-mediated signaling rely on paxillin-targeting antibodies to localize both phosphorylated and non-phosphorylated forms at adhesion plaques. Because paxillin serves as a downstream substrate for FAK and Src family kinases, the reagent is also commonly paired with phospho-enrichment or phosphatase-inhibitor lysis protocols when examining adhesion-driven phospho-signaling. Each preparation is affinity-purified and quality-controlled by Antibodies.com for reactivity with the human antigen, supporting reproducible bands on blots and clear membrane or cytoplasmic staining in immunohistochemistry.